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Showing posts with label Joy. Show all posts
Showing posts with label Joy. Show all posts

Friday, March 09, 2012

Joy in Life and its effect on Brain Centre


Joy in Life and its effect on Brain Centre

Our brain is having billions of cells cramped together in a small space in our head. But the cells do not touch each other physically. There is a gap between each cell. This gap is called as synapse. The cells are having hair like filaments by which they touch the hairlike filaments of other cells. These hairlike filaments are called dendrites. The dendrites vary from person to person, from cell to cell. They may be 50 in some cases whereas in some other cased they may be 1000. They are not fixed. And through these dendrited they are able to communicate. The scientists have not been able to ascertain as to why some neurons that is brain cells have 50 dendrites for sending messages – that is communicating with other cells while some other neurons have 10,000 dendrites. Scientists are still investigating as to why it is so. They have got one very interesting finding and which is of particular interest to us in Sri Anand Yoga. And that is thay have observed people who are mentally active – old people who are mentally active – they are actually growing new dendrites all the time. This was finding by Marian Diamond at Barkley, who had done experiments on rats and he had shown that the brains of rats grew or shrank according to the environment in which they were there. Rats which were confined to the small cages and had no social interaction, there was no fun in life as compared to the other rats – their brain, i.e. their cortexes show shrinking and they had lot of loss of dendrites. On the other hand, rats which were put back with their friends, in their society and given lot of stimulation – their brains expanded and grew more dendrites. So this gave physiological explanation as to why lonely or isolated old people are much more likely to get confused, disoriented and seem to living in void than other old people who are actively involved with family and friends.

There is one other interesting angle to this aspect. One is tempted to conclude that having more dendrited means having more developed brain. But it is not so. Very very curious and interesting observation and which in Sri Anand Yoga we are very much interested is that the babies – small babies are born with many more dendrites than their grown adults. So this is very curious. When we say that the old people get mentally active, they grow more dendrites – but babies are already having far more dendrites than the grown up people. And as they mature their dendrites fall away – their dendrites become less and less. So maturing means the lowering of the count of number of dendrites which the baby is having. Ultimately it settles to the level whereby it had whatever its needs are – in other words how much a human person is using his brain. Whatever use is there  of a person for his brain that much dendrites he will be having. We can not put any mathematical equation for this but this has been ascertained that baby is having more dendrites and it goes down and it settles as per the use of the brain and along with this we have to see that the old brains – brains of older people – they are capable of growing more dendrites as their social interaction increases.

Now why the dendrites on the brain cell of the babies are more and it goes down ? This can be compared to an experiment which we can do anywhere. Put a ball and bounce it on the floor. When we bounce it on the floor, it bounces back to almost the same height to which we bounced it. and slowly it goes on bouncing bouncing bouncing on the floor and with every bounce its height goes down down down untill  at the end of say 9th bounces it goes flat on the floor. This is like in the case of the babies. Initially we are energetic, we are active – babies want to ask so many questions, they are active, they are joyful, they are playful, they want to enjoy life – but then we put restrictions on them, we try to discipline them, we try to culture them, we try to train them in our own way. With the result we put restrictions, we tell them don’t do this, don’t do that, do this, do that – thereby killing their spontaneity of a child. And this results in a lessening of  dendrites. If we are able to bring up a child, not putting lot of restrictions on him and grooming it carefully, nurturing it with love then we will be able to keep the dendrites count at very high level. This is supported by the scientific finding. I do not know if anybody has done this experiment, but scientists have known that babies are having more dendrites and the dendrite count goes down as they grow adult.

There is a common understanding or common perception amongst scientists that our brain lose around a million neurons i.e. brain cells every year. As we grow older, the brain starts shrinking. But this is not provable because nobody can count the brain cells of a living brain. They can only have a deductive logic by having the brain weighed of a dead person and then draw conclusions out of that. But this is in doubt. It is very much in doubt whether we are really losing a million neurons every year without any replacement. We may be losong but there are replacements. Mr Robert Terry, a neuroscientist at te University of California at Santiago. He had some interesting finding in this respect. What he has observed is that there is no significant decline in neuron density in very three important areas of the brain – what he has said is that the number of large neurons does decrease but that is offset by the increase in smaller neurons. And large neurons also appear not to be dyeing but shrinking. There can not be any conclusive proof because of the limitations in doing experiments on living brain cells. But this is very interesting finding. Other neuroscientist Samuel Weiss and Brian Reynold of the University of Calgerry in Albetta – they have done experiment on brain and they have found that they can stimulate dormant brain cell to active life. What they have done  - they have cultivated mouse neurons in the laboratory and gave them a chemical called Epidermal Growth Factor causing the immature inactive brain cells to divide and form mature ones. And human brain is almost certainly storing such dormant cells for use as a replacement reserve. What we say is that we are having lot of dormant cells because of non use. We do not use full capacity of brain. We do not live our life to a full extent. That is why we are having these dormant cells. And it is possible to bring these dormant cells into life. What the scientists have done chemically we can do it without chemicals.

Brain has its own natural mechanism for activating itself in old age. It is very interesting to know that after you pass the age of 80, new dendrites grow longer and sprout more new branches. It is very interesting. It becomes more and more complex after they pass 80. So as neurons shrink, they create new synapses which in turn stimulates more endocrenical activity in the brain. There is a protein called Nerve Growth Factor (NGF). This is natural substance and this natural substance stimulate the growth and repair of a brain cell. At John Hopkins Laboratory this NGF experiment was done and it was shown that NGF prevented the degenaration of old neurons in rats and monkeys when this was injected into the brain of old rats. This improved to a very significant extent the spatial memory – i.e. memory related to the space.

The study was conducted at this university it was a very long term study and it was found out that there was no general decline in intelligence amongst old people unless they are suffering from high blood pressure. Till the age of 120 – which is our natural biological age – if we do not fall sick, we will live upto the age of 120. And scientists have more or less concluded that sickness, not the ageing process itself is to create decline in mental functioning.

Thursday, July 03, 2008

Hunger of Life ... Fountain of Youth Part II

Hunger of Life .....................................................................Shrikant Soman
Fountain of Youth - Part Two
My Experiments with Life

The Scientists have been able to extend the life span of a worm named Caenorhabditis Elegans (CE) by 6 times over. As against the normal life span of CE of 24 days, the Scientists were able to make the worm survive for 124 days. If we were able to apply the same technique to the humans, we would live for 500 to 600 years ! This feat was achieved by altering the signaling pathways for a protein called Insulin-like Growth Factor 1 (IGF-1). This same protein controls the longevity in humans. This is an extreme case of treating human body like a machine – completely and totally different and independent from our own Self. This is horrible – simply horrible. I am not talking of any ethical or moral issues involved. If we were able, with the help of science alone, to increase our life span without any corresponding life system development, it would drive us to commit suicides, get killed by accidents or kill each other in anarchy. To give you a simple example, consider the case of a car. If we were to produce a car which has an exceptionally high speed of say 400 km per hour, and if we, who are used to drive at 200 km per hour start driving the car, how far can we go ? We are already having cars which give much higher than even this speed of 400 kms. But for these cars to drive safely, we have racing car drivers and specially made racing tracks. The scientific research in all directions, including longevity research, is very helpful and good part of human development. However, if other part of our life systems does not cope with this research, it will cause stress and strains and will cause more damage than good. It will be like a very fast racing car with wrong alignment of wheels.
Interestingly, the subsequent research on CE has revealed that in much the same way that we humans do, the CE worm has sagging muscles and a growing middle as it ages. The survival does not automatically bring with it robust life system. Even if we assume that with some scientific breakthrough in future, we are able to have good muscle strength of CE worm even at its old age, still, for us the humans, the basic problem of improving the level of our life system needs to be tackled.
We need to develop our life system in a robust and healthy manner in all its aspects. The joy of life is an integral part of our life system. Without joy, what is left is only the survival. Even if we do not fall physically sick and live for say 200 years, it will still be a sick life nonetheless, unless there is a joy in life. Joy in life is in the beginning, it is in the middle and it is in the end – it is everywhere. The life of cells give a very interesting insight to the life system on a larger level.
A very important process involved in digesting the food is called ‘metabolism’. It is commonly understood that metabolism indicates uptake of nutrients from the blood and their conversion to energy usable for cellular activities. Actually metabolism involves two diverse processes – anabolism and catabolism. Anabolism is constructive metabolism. It builds up tissues by the construction of carbohydrates, proteins and fats. Anabolism is destructive metabolism. It causes the chemical breakdown of complex substances to produce energy as well as waste matter. This process of metabolism is present in our whole life system. It holds the key to good health as well as to longevity. The commonly held belief that lack of sufficient nutrients in our food causes malnutrition is absolutely wrong. It hold good only in about 5 % of the cases. In 95 % of the cases, the problem lies not in the insufficient amount of nutrients in our daily food, but in the lack of our capacity to effectively metabolise the food intake. The effectiveness of metabolism depends, among many other things, our love and respect for food and for life in general. Sri Anand Yoga has yogic practices to increase the metabolic effectiveness by many fold. It is founded on thankfulness for all the players in our Universe – our parents, the persons cooking the meal, farmers, the Mother Earth, our House and this beautiful life in general. It is powered by our ‘hunger’ for food. We need to have the same intensity of hunger as the hardworking poor man earning just enough to feed himself and his family. It is made joyful by the blessing of the food we eat. Eating food is a very important part of the life system of Sri Anand Yoga.
Adenosine Triphosphate (ATP) is a key molecule that powers our cellular activities. Cells produce ATP from glucose and glucose is derived from sugar (carbohydrates). Another key hormone is insulin. It influences the glucose used by the cells. It serve s as the key that opens the cell doors to the sugar. Metabolic processes involving glucose and insulin greatly influence life span. It is a paradox that while ATP is absolutely essential for cellular life, the abundance of it is also the cause of cell degeneration. We need to have ATP just in right quantity. The caloric restriction reduces the supply of glucose to the cells. It helps in keeping ATP in check. However, in Sri Anand Yoga, we believe that the culprit is not caloric abundance but our inability to make good of the calories available to us. Any excess amount of calories need to be thrown out of our bodily system. If we are not able to do this, the science wrongly advises us to eat less food. Overeating is certainly bad. But under-eating is equally bad. The ‘right’ quantity and type of food is not decided by any ‘table of nutrients and their calorific values’ and the ‘calorie burning’ activities. It is naturally and spontaneously decided by our body if we treat food as an integral part of our life system.
Here we again come to the black sheep ‘free radicals’. Much of the free radicals are produced by the ATP making machinery of the cells. All this leads us to the absolutely absurd and stupid hypothesis that the food we eat is the culprit. If we have this attitude towards food, how on earth can we improve our life system ? It is certainly true that meat, excessive oils, aerated soft drinks, junk food etc are bad for health. However, there is no point in making a fetish of the ‘nutrition’ theory of food.
It is interesting to learn as to how the calorie restriction is supposed to help us. The reduced amount of the food intake is taken by the body as a signal of famine. The cells then shift their gear to self-preservation mode. Its main focus now is only in cell maintenance and repair. The other major activity of reproduction is neglected. This way the cells are able to make the maximum use of the scarce energy. This hypothesis of ‘virtual famine’ in cell world is confirmed by the production of hormones that protect cells from excess heat and other stresses – similar in real life when actual famine happens. In Sri Anand Yoga, we ask the question – why the hell we have to ‘simulate famine’ in order to live longer ? Are we ‘cursed’ by the abundance of food ? The master key to this paradox lies in looking beyond ‘mathematics’ of ‘calorific values’ and into the ‘life values’ of food and everything else that this life offers us.
Similarly, insulin is essential for the cells to convert glucose into energy. Insufficient insulin will deprive us of the sufficient energy and excessive sugar in the blood. Paradoxically, the same insulin can contribute to heart disease and to undesirable cell proliferation – cancer. It is an interesting topic as to the real role of insulin in our health and life system. It will be covered sometime later. At this stage we just mention that in Sri Anand Yoga, we look beyond physical process of insulin and into the spiritual aspect of it.
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